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Biochem Soc Trans. 2010 Aug;38(4):879-82. doi: 10.1042/BST0380879.

Homomeric protein complexes: evolution and assembly.

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  • 1MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.

Abstract

Homo-oligomeric protein complexes are functionally vital and highly abundant in living cells. In the present article, we review our current understanding of their geometry and evolution, including aspects of the symmetry of these complexes and their interaction interfaces. Also, we briefly discuss the pathway of their assembly in solution.

PMID:
20658970
[PubMed - indexed for MEDLINE]
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