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Curr Biol. 2010 Jul 27;20(14):R598-600. doi: 10.1016/j.cub.2010.05.054.

MicroRNAs: genetically sensitized worms reveal new secrets.

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  • Department of Molecular Medicine, University of Massachusetts Medical School, 373 Plantation St, Worcester, MA 01605, USA. victor.ambros@umassmed.edu

Abstract

Why do many microRNA gene mutants display no evident phenotype? Multiply mutant worms that are selectively impaired in genetic regulatory network activities have been used to uncover previously unknown functions for numerous Caenorhabditis elegans microRNAs.

2010 Elsevier Ltd. All rights reserved.

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PMID:
20656201
[PubMed - indexed for MEDLINE]
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