Candidal arthritis in revision knee arthroplasty successfully treated with sequential parenteral-oral fluconazole and amphotericin B-loaded cement spacer

Meng-Huang Wu; Kuo-Yao Hsu

doi:10.1007/s00167-010-1211-4

Candidal arthritis in revision knee arthroplasty successfully treated with sequential parenteral-oral fluconazole and amphotericin B-loaded cement spacer

Knee Surg Sports Traumatol Arthrosc. 2011 Feb;19(2):273-6. doi: 10.1007/s00167-010-1211-4. Epub 2010 Jul 22.

Authors

Meng-Huang Wu¹, Kuo-Yao Hsu

Affiliation

¹ Department of Orthopedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.

PMID: 20652534
DOI: 10.1007/s00167-010-1211-4

Abstract

We present a case of a patient with preoperative cutaneous candidiasis, who developed candidal infection during stage revision knee arthroplasty. The patient received intravenous fluconazole for 6 weeks and resection arthroplasty with an amphotericin B-loaded cement spacer and continuous oral fluconazole therapy for 9 weeks. Revision surgery was successful.

Publication types

Case Reports

MeSH terms

Administration, Oral
Aged
Amphotericin B / administration & dosage*
Antifungal Agents / administration & dosage*
Arthritis, Infectious / drug therapy*
Arthroplasty, Replacement, Knee
Bone Cements
Candidiasis / drug therapy*
Fluconazole / administration & dosage*
Humans
Infusions, Parenteral
Knee Joint / diagnostic imaging
Knee Prosthesis / adverse effects*
Male
Prosthesis-Related Infections / drug therapy*
Radiography
Reoperation

Substances

Antifungal Agents
Bone Cements
Amphotericin B
Fluconazole