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BMC Biol. 2010 Jul 13;8:90. doi: 10.1186/1741-7007-8-90.

Genome-wide association studies in Plasmodium species.

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  • 1Department of Zoology, University of Oxford, Oxford OX1 3PS, UK.

Abstract

Genome-wide association studies (GWAS) look for correlations between traits of interest and genetic markers spread throughout the genome. A recent study in BMC Genetics has found that populations of the malaria parasite Plasmodium vivax should be amenable to GWAS searching for a genetic basis of parasite pathogenicity. Geographical substructure in populations may, however, prove a problem in interpreting the results.

PMID:
20646263
[PubMed - indexed for MEDLINE]
PMCID:
PMC2903549
Free PMC Article
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