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Pharm Biol. 2010 Feb;48(2):151-7. doi: 10.3109/13880200903062614.

Anti-inflammatory, analgesic, and antipyretic activities of virgin coconut oil.

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  • 1McCormick Faculty of Nursing, Payap University, Chiang Mai, Thailand. sophaphan_in@yahoo.com

Abstract

This study investigated some pharmacological properties of virgin coconut oil (VCO), the natural pure oil from coconut [Cocos nucifera Linn (Palmae)] milk, which was prepared without using chemical or high-heat treatment. The anti-inflammatory, analgesic, and antipyretic effects of VCO were assessed. In acute inflammatory models, VCO showed moderate anti-inflammatory effects on ethyl phenylpropiolate-induced ear edema in rats, and carrageenin- and arachidonic acid-induced paw edema. VCO exhibited an inhibitory effect on chronic inflammation by reducing the transudative weight, granuloma formation, and serum alkaline phosphatase activity. VCO also showed a moderate analgesic effect on the acetic acid-induced writhing response as well as an antipyretic effect in yeast-induced hyperthermia. The results obtained suggest anti-inflammatory, analgesic, and antipyretic properties of VCO.

PMID:
20645831
[PubMed - indexed for MEDLINE]
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