Arch Dermatol. 1991 Jul;127(7):1034-40.

Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature.

Zic JA, Horowitz DH, Arzubiaga C, King LE Jr.

Source

Division of Dermatology, Vanderbilt School of Medicine, Nashville, Tenn. 37232.

Abstract

Systemic corticosteroids may be either contraindicated or not efficacious in treating the cutaneous manifestations occurring in 20% to 35% of patients with systemic sarcoidosis. Chloroquine phosphate has been reported to be a valuable alternative therapy for cutaneous lesions of sarcoidosis. With a judiciously determined daily dosage and regular 6-month ophthalmologic follow-up examinations, the risk of developing retinopathy can be avoided, because the daily dosage rate rather than total dose accumulation determines the development of chloroquine-induced retinopathy. We reviewed the efficacy and safety of chloroquine and its role in the treatment of cutaneous sarcoidosis.

PMID:: 2064404; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Chloroquine

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Molecular Biology Databases

CHLOROQUINE - HSDB

Supplemental Content

Icon for Silverchair Information Systems

Save items

Related citations in PubMed

Chloroquine therapy in 43 patients with intrathoracic and cutaneous sarcoidosis. [Acta Med Scand Suppl. 1964]
Chloroquine therapy in 43 patients with intrathoracic and cutaneous sarcoidosis.
Siltzbach LE, Teirstein AS. Acta Med Scand Suppl. 1964; 425:302-8.
The effects of chloroquine on serum 1,25-dihydroxyvitamin D and calcium metabolism in sarcoidosis. [N Engl J Med. 1986]
The effects of chloroquine on serum 1,25-dihydroxyvitamin D and calcium metabolism in sarcoidosis.
O'Leary TJ, Jones G, Yip A, Lohnes D, Cohanim M, Yendt ER. N Engl J Med. 1986 Sep 18; 315(12):727-30.
Effectiveness of chloroquine and hydroxychloroquine in treating selected patients with sarcoidosis with neurological involvement. [Arch Neurol. 1998]
Effectiveness of chloroquine and hydroxychloroquine in treating selected patients with sarcoidosis with neurological involvement.
Sharma OP. Arch Neurol. 1998 Sep; 55(9):1248-54.
Review Evidence-based therapy for cutaneous sarcoidosis. [Drugs. 2008]
Review Evidence-based therapy for cutaneous sarcoidosis.
Doherty CB, Rosen T. Drugs. 2008; 68(10):1361-83.
Review [Synthetic antimalarials]. [Ann Dermatol Venereol. 2005]
Review [Synthetic antimalarials].
Fardet L, Revuz J. Ann Dermatol Venereol. 2005 Aug-Sep; 132(8-9 Pt 1):665-74.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature.
Treatment of cutaneous sarcoidosis with chloroquine. Review of the literature.
Arch Dermatol. 1991 Jul ;127(7):1034-40.

PubMed
Octocrylene, an emerging photoallergen.
Octocrylene, an emerging photoallergen.
Arch Dermatol. 2010 Jul ;146(7):753-7.

PubMed
Relationship between nonsustained ventricular tachycardia after non-ST-elevation...
Relationship between nonsustained ventricular tachycardia after non-ST-elevation acute coronary syndrome and sudden cardiac death: observations from the metabolic efficiency with ranolazine for less ischemia in non-ST-elevation acute coronary syndrome-thrombolysis in myocardial infarction 36 (MERLIN-TIMI 36) randomized controlled trial.
Circulation. 2010 Aug 3 ;122(5):455-62. Epub 2010 Jul 19 .

PubMed
Successful use of topical vitamin E solution in the treatment of nail changes in...
Successful use of topical vitamin E solution in the treatment of nail changes in yellow nail syndrome.
Arch Dermatol. 1991 Jul ;127(7):1023-8.

PubMed
Simvastatin ameliorates rat cerebrovascular remodeling during hypertension via i...
Simvastatin ameliorates rat cerebrovascular remodeling during hypertension via inhibition of volume-regulated chloride channel.
Hypertension. 2010 Sep ;56(3):445-52. Epub 2010 Jul 19 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: