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    Results: 7

    1.

    HERC2 is an E3 ligase that targets BRCA1 for degradation.

    Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T.

    Cancer Res. 2010 Aug 1;70(15):6384-92. Epub 2010 Jul 14.

    PMID:
    20631078
    [PubMed - indexed for MEDLINE]
    Free Article
    2.

    The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.

    Wu-Baer F, Ludwig T, Baer R.

    Mol Cell Biol. 2010 Jun;30(11):2787-98. Epub 2010 Mar 29.

    PMID:
    20351172
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.

    Ueki T, Park JH, Nishidate T, Kijima K, Hirata K, Nakamura Y, Katagiri T.

    Cancer Res. 2009 Nov 15;69(22):8752-60. Epub 2009 Nov 3.

    PMID:
    19887602
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.

    Sobhian B, Shao G, Lilli DR, Culhane AC, Moreau LA, Xia B, Livingston DM, Greenberg RA.

    Science. 2007 May 25;316(5828):1198-202.

    PMID:
    17525341
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Ubiquitin transfer from the E2 perspective: why is UbcH5 so promiscuous?

    Brzovic PS, Klevit RE.

    Cell Cycle. 2006 Dec;5(24):2867-73. Epub 2006 Dec 8.

    PMID:
    17218787
    [PubMed - indexed for MEDLINE]
    Free Article
    6.

    Ubiquitination and proteasome-mediated degradation of BRCA1 and BARD1 during steroidogenesis in human ovarian granulosa cells.

    Lu Y, Amleh A, Sun J, Jin X, McCullough SD, Baer R, Ren D, Li R, Hu Y.

    Mol Endocrinol. 2007 Mar;21(3):651-63. Epub 2006 Dec 21.

    PMID:
    17185394
    [PubMed - indexed for MEDLINE]
    Free Article
    7.

    Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.

    Hayami R, Sato K, Wu W, Nishikawa T, Hiroi J, Ohtani-Kaneko R, Fukuda M, Ohta T.

    Cancer Res. 2005 Jan 1;65(1):6-10.

    PMID:
    15665273
    [PubMed - indexed for MEDLINE]
    Free Article

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