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J Pediatr Hematol Oncol. 2010 Aug;32(6):e241-3. doi: 10.1097/MPH.0b013e3181e5e25b.

Successful treatment of late, recurrent wilms tumor with high-dose chemotherapy and autologous stem cell rescue in third complete response.

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  • 1Division of Pediatric Hematology/Oncology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA.



Wilms tumor relapses are infrequent, occurring in approximately 15% of favorable histology patients. Very few cases of late recurrent relapse exist in the literature. Long-term survival after autologous stem cell rescue ranges from 40% to 73%, but there are very few reports of patients transplanted in their third complete response. We report a late recurrent relapse of Wilms tumor successfully treated with high-dose chemotherapy and autologous stem cell rescue in his third complete response who remains disease free 15 months posttransplant.

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