Format

Send to:

Choose Destination
See comment in PubMed Commons below
Duodecim. 2010;126(12):1487-95.

[Biological therapy in rheumatoid arthritis based on ten years of registry surveillance in Finland].

[Article in Finnish]

Author information

  • 1HYKS:n yleissisätautien ja reumatologian klinikka, PL 340, 00029 HUS.

Abstract

Biological drugs are used in the treatment of active inflammatory athritides refractory to conventional treatment. Data from the Finnish registry of biological treatment (ROB-FIN) indicates that the effectiveness of the biologicals in clinical practice corresponds to or even excels that of randomized controlled clinical trials, and seems to endure in patients continuing treatment. About one-fifth of rheumatoid arthritis patients discontinue treatment due to lack of effectiveness, and one-tenth due to adverse events. Serious adverse events were seen in 2.5% of all patients. In the future electronic follow-up, pharmacogenetics, and biomarker research may help to better optimize treatment individually.

PMID:
20617752
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk