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Int J Environ Res Public Health. 2010 Apr;7(4):1486-99. doi: 10.3390/ijerph7041486. Epub 2010 Mar 31.

Air pollution exposure--a trigger for myocardial infarction?

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  • 1Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm,


The association between ambient air pollution exposure and hospitalization for cardiovascular events has been reported in several studies with conflicting results. A case-crossover design was used to investigate the effects of air pollution in 660 first-time myocardial infarction cases in Stockholm in 1993-1994, interviewed shortly after diagnosis using a standard protocol. Air pollution data came from central urban background monitors. No associations were observed between the risk for onset of myocardial infarction and two-hour or 24-hour air pollution exposure. No evidence of susceptible subgroups was found. This study provides no support that moderately elevated air pollution levels trigger first-time myocardial infarction.


air pollution; case cross-over design; myocardial infarction; onset; trigger

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