Your browser version may not work well with NCBI's Web applications. More information here...
1: Epilepsy Res. 1991 Jan-Feb;8(1):75-8.Click here to read Links

Serum folic acid levels in epileptic mothers and their relationship to congenital malformations.

Ogawa Y, Kaneko S, Otani K, Fukushima Y.

Department of Obstetrics and Gynecology, Mutsu General Hospital, Japan.

Folic acid levels during pregnancy and in pre-pregnancy were determined in 51 epileptic mothers and those of matched controls. The serum folic acid (SF) levels of epileptic mothers were significantly lower than those of controls in all study periods. The SF levels of mothers of malformed offspring were significantly lower than those of mothers of normal offspring in the 1st and 2nd trimesters of pregnancy. These results suggest that SF concentrations are implicated in congenital malformations in the offspring of epileptic mothers.

PMID: 2060505 [PubMed - indexed for MEDLINE]

Related Articles

Patient Drug Information
  • Folic Acid (Folvite®) Folic acid is used to treat or prevent folic acid deficiency. It is a B-complex vitamin needed by the body to manufacture red blood cells. A deficiency of this vitamin causes certain types of anemia (low red blood cell c...
    » read more ...