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1.

Heteroaromatic 4-arylquinols are novel inducers of nuclear factor-erythroid 2-related factor 2 (Nrf2).

Wong DP, Wells G, Hagen T.

Eur J Pharmacol. 2010 Sep 25;643(2-3):188-94. Epub 2010 Jun 30.

PMID:: 20599909; [PubMed - indexed for MEDLINE]

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2.

An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.

Kaspar JW, Jaiswal AK.

J Biol Chem. 2010 Jul 9;285(28):21349-58. Epub 2010 May 7.

PMID:: 20452971; [PubMed - indexed for MEDLINE]

Free PMC Article

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3.

A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.

Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD.

Mol Cell Biol. 2010 Jul;30(13):3275-85. Epub 2010 Apr 26.

PMID:: 20421418; [PubMed - indexed for MEDLINE]

Free PMC Article

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4.

Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance.

Niture SK, Jain AK, Jaiswal AK.

J Cell Sci. 2009 Dec 15;122(Pt 24):4452-64. Epub 2009 Nov 17. Erratum in: J Cell Sci. 2010 Jun;123(Pt 11):1969.

PMID:: 19920073; [PubMed - indexed for MEDLINE]

Free PMC Article

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5.

Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs.

Patel R, Maru G.

Free Radic Biol Med. 2008 Jun 1;44(11):1897-911. Epub 2008 Feb 21.

PMID:: 18358244; [PubMed - indexed for MEDLINE]

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6.

Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin.

Tanigawa S, Fujii M, Hou DX.

Free Radic Biol Med. 2007 Jun 1;42(11):1690-703. Epub 2007 Feb 28.

PMID:: 17462537; [PubMed - indexed for MEDLINE]

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7.

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.

He X, Chen MG, Lin GX, Ma Q.

J Biol Chem. 2006 Aug 18;281(33):23620-31. Epub 2006 Jun 19.

PMID:: 16785233; [PubMed - indexed for MEDLINE]

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8.

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation.

Hong F, Sekhar KR, Freeman ML, Liebler DC.

J Biol Chem. 2005 Sep 9;280(36):31768-75. Epub 2005 Jun 28.

PMID:: 15985429; [PubMed - indexed for MEDLINE]

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9.

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.

Zhang DD, Lo SC, Sun Z, Habib GM, Lieberman MW, Hannink M.

J Biol Chem. 2005 Aug 26;280(34):30091-9. Epub 2005 Jun 27.

PMID:: 15983046; [PubMed - indexed for MEDLINE]

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10.

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M.

Mol Cell Biol. 2004 Dec;24(24):10941-53.

PMID:: 15572695; [PubMed - indexed for MEDLINE]

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