Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
BMC Biol. 2010 Jun 11;8:74. doi: 10.1186/1741-7007-8-74.

The (r)evolution of cancer genetics.

Author information

  • Department of Experimental Oncology, European Institute of Oncology, IFOM-IEO Campus, 20139 Milan, Italy. francesca.ciccarelli@ifom-ieo-campus.it

Abstract

The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation. A recent paper published in BMC Biology shows how the founder domains of known cancer genes emerged at two macroevolutionary transitions - the advent of the first cell and the transition to metazoan multicellularity. See research article http://www.biomedcentral.com/1741-7007/8/66.

Comment on

PMID:
20594288
[PubMed - indexed for MEDLINE]
PMCID:
PMC2883958
Free PMC Article

Images from this publication.See all images (1)Free text

Figure 1
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Write to the Help Desk