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Ultrastruct Pathol. 2010 Aug;34(4):240-2. doi: 10.3109/01913121003783209.

Fibronectin glomerulopathy in a 34-year-old man: a case report.

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  • 1Clinical Department of Pathology and Cytology, University Hospital Center Zagreb, Zagreb, Croatia.

Abstract

Fibronectin glomerulopathy is an inherited non-immune-mediated glomerulopathy associated with the massive deposition of fibronectin. It presents with proteinuria, microscopic hematuria, and hypertension that lead to end-stage renal failure in the second to sixth decade of life. A 34-year-old male was referred with proteinuria (6 g/day), microscopic hematuria and hypertension (220/130 mmHg). Renal biopsy specimen showed massive deposits of fibronectin in the mesangium and subendothelial spaces. After 20 months of multidrug treatment his renal function is stable.

PMID:
20594046
[PubMed - indexed for MEDLINE]
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