Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Eur J Radiol. 2011 Nov;80(2):e8-12. doi: 10.1016/j.ejrad.2010.05.042. Epub 2010 Jun 26.

Ileal Crohn's disease: MRI with endoscopic correlation.

Author information

  • 1Department of Radiology, Hospital A. Marcide, Ferrol, Spain. josecarlos.gallego.ojea@sergas.es

Abstract

PURPOSE:

To evaluate activity staging of Crohn's disease (CD) measured with MR-enterography using ileoscopy as reference standard.

MATERIALS AND METHODS:

A prospective study was made of 61 patients with CD. All patients underwent MR-enterography and ileoscopy. MRI activity was measured by means of an ad hoc developed score, as well as by analysis of the imaging findings, and was compared with the SES-CD score obtained via ileoscopy. Examinations were performed using a 1.0 T scanner.

RESULTS:

MRI score discriminates between active and inactive disease with an area under the ROC curve of 0.941. Overall correlation with the standard reference SES-CD score was moderate to strong (Spearman's r=0.62 p<0.001). Agreement between both methods in staging patients with ileal CD as inactive, mild or moderate to severe was good (Cohen's κ=0.60). Differences in means of the MRI activity scores of the three groups showed statistical significance (p<0.01).

CONCLUSIONS:

The MRI score is a reliable predictor of activity in ileal CD and can stage patients in a way comparable to endoscopy. 1.0 T scans are valid for performing radiological evaluation of ileal Crohn's disease.

Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

PMID:
20580178
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk