Sci Signal. 2010 Jun 22;3(127):eg4.

(R)evolution of complex regulatory systems.

Abstract

Signaling systems are exciting to study precisely because they are some of the most complex and dynamical systems that we know. The cell needs operational freedom and, thus, many motif-domain interactions might not be "hard-wired" through evolution, but instead may be like the Linux operating system, where symbolic links can point to files without duplication.

PMID:: 20571125; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Editorial

MeSH Terms

Substances

Proteome

LinkOut - more resources

Full Text Sources

HighWire Press

Supplemental Content

Related citations

Cell++--simulating biochemical pathways. [Bioinformatics. 2006]
Cell++--simulating biochemical pathways.
Sanford C, Yip ML, White C, Parkinson J. Bioinformatics. 2006 Dec 1; 22(23):2918-25. Epub 2006 Oct 11.
Review Models for synthetic biology. [BMC Syst Biol. 2007]
Review Models for synthetic biology.
Kaznessis YN. BMC Syst Biol. 2007 Nov 6; 1:47. Epub 2007 Nov 6.
Review Systems biology in drug discovery. [Conf Proc IEEE Eng Med Biol Soc. 2006]
Review Systems biology in drug discovery.
Kunkel EJ. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:37.
Synthetic biology: designs on life. [Nature. 2005]
Synthetic biology: designs on life.
Check E. Nature. 2005 Nov 24; 438(7067):417-8.
Pathway classification of TCA cycle. [Syst Biol (Stevenage). 2006]
Pathway classification of TCA cycle.
Pérès S, Beurton-Aimar M, Mazat JP. Syst Biol (Stevenage). 2006 Sep; 153(5):369-71.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

(R)evolution of complex regulatory systems.
(R)evolution of complex regulatory systems.
Sci Signal. 2010 Jun 22 ;3(127):eg4.

PubMed
Body image and first sexual intercourse in late adolescence.
Body image and first sexual intercourse in late adolescence.
J Adolesc. 2011 Apr ;34(2):327-35. Epub 2010 May 21 .

PubMed
Differentiation of chronic sinus diseases by measurement of inflammatory mediato...
Differentiation of chronic sinus diseases by measurement of inflammatory mediators.
Allergy. 2006 Nov ;61(11):1280-9.

PubMed
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosi...
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells.
Cancer Res. 2009 Jun 15 ;69(12):5015-22. Epub 2009 Jun 2 .

PubMed
Zidovudine triphosphate and lamivudine triphosphate concentration-response relat...
Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.
AIDS. 2000 Sep 29 ;14(14):2137-44.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

(R)evolution of complex regulatory systems.

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Supplemental Content

Related citations

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information