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Genome Biol. 2010;11(6):123. doi: 10.1186/gb-2010-11-6-123. Epub 2010 Jun 21.

MicroRNA processing without Dicer.

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  • 1Laboratory of RNA Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany.

Abstract

The canonical processing of precursor microRNAs requires the endonuclease Dicer. A recent study shows that microRNAs can be processed independently of Dicer but instead require Argonaute 2.

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PMID:
20565849
[PubMed]
PMCID:
PMC2911099
Free PMC Article

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