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AJNR Am J Neuroradiol. 2010 Sep;31(8):1383-4. doi: 10.3174/ajnr.A2170. Epub 2010 Jun 10.

Temozolomide (Temodar).

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  • 1University of Michigan Medical Center, Ann Arbor, MI, USA. jefwesol@med.umich.edu

Abstract

Temozolomide, an oral alkylating agent, is a commonly used medicine in the treatment of anaplastic astrocytoma and glioblastoma multiforme. This paper will present the mechanism of action as well as the clinical role for this chemotherapeutic drug.

PMID:
20538821
[PubMed - indexed for MEDLINE]
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