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Nucleic Acids Res. 2010 Jul;38(Web Server issue):W743-8. doi: 10.1093/nar/gkq538. Epub 2010 Jun 8.

ZOOM Lite: next-generation sequencing data mapping and visualization software.

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  • 1Bioinformatics Solutions Inc., Waterloo, ON N2L 6J2, Canada.

Abstract

High-throughput next-generation sequencing technologies pose increasing demands on the efficiency, accuracy and usability of data analysis software. In this article, we present ZOOM Lite, a software for efficient reads mapping and result visualization. With a kernel capable of mapping tens of millions of Illumina or AB SOLiD sequencing reads efficiently and accurately, and an intuitive graphical user interface, ZOOM Lite integrates reads mapping and result visualization into a easy to use pipeline on desktop PC. The software handles both single-end and paired-end reads, and can output both the unique mapping result or the top N mapping results for each read. Additionally, the software takes a variety of input file formats and outputs to several commonly used result formats. The software is freely available at http://bioinfor.com/zoom/lite/.

PMID:
20530531
[PubMed - indexed for MEDLINE]
PMCID:
PMC2896157
Free PMC Article

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