Abstract
The reaction between phthalylsulfathiazole (H(2)PST), in alkaline aqueous solution, and cobalt(II) nitrate led to a pink solid, [Co(PST)(H(2)O)(4)] (1), which was characterized by elemental and thermogravimetric analysis; FT-IR, Raman and diffuse reflectance spectra. Spectroscopic data reveal that the ligand would be doubly deprotonated and that the Co(II) ion environment is a distorted octahedral one. (1) showed antibacterial activity similar to the ligand.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / chemical synthesis*
-
Anti-Bacterial Agents / chemistry
-
Anti-Bacterial Agents / pharmacology*
-
Antifungal Agents / chemical synthesis
-
Antifungal Agents / chemistry
-
Antifungal Agents / pharmacology
-
Cobalt / chemistry*
-
Coordination Complexes / chemical synthesis*
-
Coordination Complexes / chemistry
-
Coordination Complexes / pharmacology*
-
Hemolysis / drug effects
-
Humans
-
Microbial Sensitivity Tests
-
Molecular Structure
-
Mutagenicity Tests
-
Onions / drug effects
-
Onions / genetics
-
Spectroscopy, Fourier Transform Infrared
-
Spectrum Analysis, Raman
Substances
-
Anti-Bacterial Agents
-
Antifungal Agents
-
Coordination Complexes
-
Cobalt
-
cobaltous nitrate