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Ann Plast Surg. 2010 Jun;64(6):803-6.

Beckwith-Wiedemann syndrome and juvenile fibroadenoma: a case report.

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  • 1Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232-2345, USA.


Beckwith-Wiedemann syndrome (BWS) is a complex overgrowth disorder usually recognized at birth. Children diagnosed with BWS, particularly those with hemihypertrophy, experience an increased risk of developing benign and malignant tumors. This case report presents a 12-year-old girl with BWS and hemihypertrophy who rapidly developed enlarging, asymmetric tumors of bilateral breasts. Few cases of patients with BWS and benign breast tumors exist in the literature. The differential diagnosis of breast tumors in the adolescent female is described. The treatment plan and reconstruction options particular to the developing young female are also discussed.

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