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Nucleic Acids Res. 2010 Jul;38(Web Server issue):W667-70. doi: 10.1093/nar/gkq446. Epub 2010 May 25.

GlycoViewer: a tool for visual summary and comparative analysis of the glycome.

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  • 1Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, NSW 2052, Australia.

Abstract

The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and disease-associated glycans from the human glycoproteome.

PMID:
20501599
[PubMed - indexed for MEDLINE]
PMCID:
PMC2896138
Free PMC Article

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