Photochem Photobiol. 2010 Jul-Aug;86(4):890-4. Epub 2010 May 21.

Fiber-optic singlet oxygen [1O2 (1Delta(g))] generator device serving as a point selective sterilizer.

Aebisher D, Zamadar M, Mahendran A, Ghosh G, McEntee C, Greer A.

Source

Department of Chemistry, Graduate Center & The City University of New York, Brooklyn College, Brooklyn, NY, USA.

Abstract

Traditionally, Type II heterogeneous photo-oxidations produce singlet oxygen via external irradiation of a sensitizer and external supply of ground-state oxygen. A potential improvement is reported here. A hollow-core fiber-optic device was developed with an "internal" supply of light and flowing oxygen, and a porous photosensitizer-end capped configuration. Singlet oxygen was delivered through the fiber tip. The singlet oxygen steady-state concentration in the immediate vicinity of the probe tip was ca 20 fm by N-benzoyl-DL-methionine trapping. The device is portable and the singlet oxygen-generating tip is maneuverable, which opened the door to simple disinfectant studies. Complete Escherichia coli inactivation was observed in 2 h when the singlet oxygen sensitizing probe tip was immersed in 0.1 mL aqueous samples of 0.1-4.4 x 10(7) cells. Photobleaching of the probe tip occurred after ca 12 h of use, requiring baking and sensitizer reloading steps for reuse.

PMID:: 20497367; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

OXYGEN - HSDB

Supplemental Content

Related citations

Singlet oxygen delivery through the porous cap of a hollow-core fiber optic device. [J Phys Chem B. 2009]
Singlet oxygen delivery through the porous cap of a hollow-core fiber optic device.
Zamadar M, Aebisher D, Greer A. J Phys Chem B. 2009 Dec 3; 113(48):15803-6.
Singlet oxygen chemistry in water: a porous vycor glass-supported photosensitizer. [J Phys Chem B. 2008]
Singlet oxygen chemistry in water: a porous vycor glass-supported photosensitizer.
Aebisher D, Azar NS, Zamadar M, Gandra N, Gafney HD, Gao R, Greer A. J Phys Chem B. 2008 Feb 21; 112(7):1913-7. Epub 2008 Jan 29.
A hand-held fiber-optic implement for the site-specific delivery of photosensitizer and singlet oxygen. [Photochem Photobiol. 2011]
A hand-held fiber-optic implement for the site-specific delivery of photosensitizer and singlet oxygen.
Mahendran A, Kopkalli Y, Ghosh G, Ghogare A, Minnis M, Kruft BI, Zamadar M, Aebisher D, Davenport L, Greer A. Photochem Photobiol. 2011 Nov-Dec; 87(6):1330-7. Epub 2011 Aug 31.
Review Singlet oxygen in photosensitization. [J Environ Pathol Toxicol Oncol. 2006]
Review Singlet oxygen in photosensitization.
Moan J, Juzenas P. J Environ Pathol Toxicol Oncol. 2006; 25(1-2):29-50.
Review Control and selectivity of photosensitized singlet oxygen production: challenges in complex biological systems. [Chembiochem. 2007]
Review Control and selectivity of photosensitized singlet oxygen production: challenges in complex biological systems.
Cló E, Snyder JW, Ogilby PR, Gothelf KV. Chembiochem. 2007 Mar 26; 8(5):475-81.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Fiber-optic singlet oxygen [1O2 (1Delta(g))] generator device serving as a point...
Fiber-optic singlet oxygen [1O2 (1Delta(g))] generator device serving as a point selective sterilizer.
Photochem Photobiol. 2010 Jul-Aug ;86(4):890-4. Epub 2010 May 21 .

PubMed
An SCN9A channelopathy causes congenital inability to experience pain.
An SCN9A channelopathy causes congenital inability to experience pain.
Nature. 2006 Dec 14 ;444(7121):894-8.

PubMed
Full breastfeeding duration and associated decrease in respiratory tract infecti...
Full breastfeeding duration and associated decrease in respiratory tract infection in US children.
Pediatrics. 2006 Feb ;117(2):425-32.

PubMed
Interferon lambda as a potential new therapeutic for hepatitis C.
Interferon lambda as a potential new therapeutic for hepatitis C.
Ann N Y Acad Sci. 2009 Dec ;1182:80-7.

PubMed
Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in pat...
Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection.
Hepatology. 2010 Sep ;52(3):822-32.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: