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Rev Cardiovasc Med. 2010 Winter;11(1):26-32.

Pitavastatin: the newest HMG-CoA reductase inhibitor.

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  • 1The David Geffen School of Medicine, UCLA Preventative Cardiology Program, University of California at Los Angeles, Los Angeles, CA, USA.


Statins were first introduced in the 1980s as a treatment of hypercholesterolemia. They provide a remarkable array of clinical benefits, including the reduction of low-density lipoprotein cholesterol, total cholesterol, and triglycerides, and elevation of high-density lipoprotein cholesterol. The US Food and Drug Administration has recently approved a new statin-pitavastatin-for launch in 2010. In several clinical trials, pitavastatin has shown favorable clinical efficacy, a positive safety profile, and encouraging clinical experience in Japan and other parts of Asia.

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