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FEBS Lett. 2010 Jul 2;584(13):2748-58. doi: 10.1016/j.febslet.2010.05.012. Epub 2010 May 21.

Post-translational modifications in host cells during bacterial infection.

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  • 1Institut Pasteur, Unité des Interactions Bactéries-Cellules, Département de Biologie Cellulaire et Infection, Paris, France.


Post-translational modification of proteins is a widespread mechanism used by both prokaryotic and eukaryotic cells to modify the activity of key factors that plays fundamental roles in cellular physiology. This review focuses on how bacterial pathogens can interfere with host post-translational modifications to promote their own survival and replication.

Copyright 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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