Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Dermatitis. 2010 May-Jun;21(3):148-53.

Vitamin E and allergic contact dermatitis.

Author information

  • 1Center for Dermatology Research, Departments of Dermatology, Pathology, and Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1071, USA.


Reports of vitamin E-induced allergic contact dermatitis (ACD) and frequent use of vitamin-E derivatives (tocopherol, tocopheryl linoleate, tocopherol acetate, etc) in skin care products deserves further investigation into tolerability and suitability of vitamin E in skin care preparations. A PubMed search was conducted to review the prevalence of vitamin E-induced ACD. It revealed 931 cases of vitamin E-induced ACD mainly from one large study. There were no reported deaths and only three patients required hospitalization for treatment. It appears that vitamin E-induced ACD is an uncommon phenomenon; incidence is low despite its widespread use in skin care products. Given its antioxidant and photoprotective properties, vitamin E should remain an ingredient in skin care products.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Write to the Help Desk