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Vaccine. 2010 Jul 12;28(31):4875-9. doi: 10.1016/j.vaccine.2010.05.002. Epub 2010 May 16.

A computer simulation of vaccine prioritization, allocation, and rationing during the 2009 H1N1 influenza pandemic.

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  • 1University of Pittsburgh, Pittsburgh, PA 15213, USA.


In the fall 2009, the University of Pittsburgh Models of Infectious Disease Agent Study (MIDAS) team employed an agent-based computer simulation model (ABM) of the greater Washington, DC, metropolitan region to assist the Office of the Assistant Secretary of Public Preparedness and Response, Department of Health and Human Services, to address several key questions regarding vaccine allocation during the 2009 H1N1 influenza pandemic, including comparing a vaccinating children (i.e., highest transmitters)-first policy versus the Advisory Committee on Immunization Practices (ACIP)-recommended vaccinating at-risk individuals-first policy. Our study supported adherence to the ACIP (instead of a children-first policy) prioritization recommendations for the H1N1 influenza vaccine when vaccine is in limited supply and that within the ACIP groups, children should receive highest priority.

Copyright 2010 Elsevier Ltd. All rights reserved.

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