J Photochem Photobiol B. 2010 Nov 3;101(2):137-41. Epub 2010 Apr 21.

The role of vitamin D in multiple sclerosis.

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University Hospital of North Norway, Department of Neurology, P.O. Box 6060, 9038 Tromsø, Norway. margitta.kampman@unn.no

Abstract

Multiple sclerosis (MS) risk is determined by environmental influences acting on the individual genetic background. Recent epidemiologic and experimental evidence supports a role of low environmental supplies of vitamin D in mediating an increased susceptibility to MS. We review available evidence suggesting that vitamin D status may influence MS risk and even modulate clinical disease activity. The level of serum 25-hydroxyvitamin D providing these effects remains to be determined.

PMID:: 20471852; [PubMed - indexed for MEDLINE]

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