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Infect Dis Clin North Am. 2010 Jun;24(2):373-93. doi: 10.1016/j.idc.2010.01.003.

Herpes viruses in transplant recipients: HSV, VZV, human herpes viruses, and EBV.

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  • 1Division of Infectious Diseases, Hospital of the University of Pennsylvania, 3rd Floor Silverstein Pavilion, Suite E, 3400 Spruce Street, Philadelphia, PA 19104, USA.


The herpes viruses are responsible for a wide range of diseases in patients following transplant, resulting from direct viral effects and indirect effects, including tumor promotion. Effective treatments and prophylaxis exist for the neurotropic herpes viruses HSV-1, HSV-2, varicella zoster virus, and possibly HHV-6. Antivirals seem to be less effective at prevention of the tumor-promoting effects of Epstein-Barr virus and HHV-8. Reduction in immunosuppression is the cornerstone to treatment of many diseases associated with herpes virus infections.

Copyright (c) 2010 Elsevier Inc. All rights reserved.

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