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Diabetes Care. 2010 Jul;33(7):1652-4. doi: 10.2337/dc10-0107. Epub 2010 May 11.

Sarcopenic obesity: prevalence and association with metabolic syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA).

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  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

Abstract

OBJECTIVE:

We investigated the prevalence of sarcopenic obesity (SO) and its relationship with metabolic syndrome in a community-based elderly cohort in Korea.

RESEARCH DESIGN AND METHODS:

In this study, 287 men and 278 women aged 65 or older were recruited. Sarcopenia was defined as the appendicular skeletal muscle mass (ASM) divided by height squared (Ht(2)) (kg/m(2)) or by weight (Wt) (%) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a visceral fat area >or=100 cm(2).

RESULTS:

The prevalence of SO was 16.7% in men and 5.7% in women with sarcopenia defined by ASM/Ht(2); however, it was 35.1% in men and 48.1% in women by ASM/Wt. Using ASM/Wt, the homeostasis model assessment of insulin resistance of subjects with SO was higher and they were at higher risk for metabolic syndrome (odds ratio [OR] 8.28 [95% CI 4.45-15.40]) than the obese (5.51 [2.81-10.80]) or sarcopenic group (2.64 [1.08-6.44]).

CONCLUSIONS:

SO defined by ASM/Wt was more closely associated with metabolic syndrome than either sarcopenia or obesity alone.

PMID:
20460442
[PubMed - indexed for MEDLINE]
PMCID:
PMC2890376
Free PMC Article
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