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J Biomed Opt. 2010 Mar-Apr;15(2):021304. doi: 10.1117/1.3339953.

Transverse flow imaging based on photoacoustic Doppler bandwidth broadening.

Author information

  • 1Washington University in St. Louis, Department of Biomedical Engineering, Optical Imaging Laboratory, Campus Box 1097, One Brookings Drive, St. Louis, Missouri 63130, USA.

Abstract

We propose a new method to measure transverse flow velocity based on photoacoustic Doppler bandwidth broadening, which is determined by the geometry of the probe-beam and the velocity of the transverse flow. By exploiting pulsed laser excitation and raster motor scanning, three-dimensional structure and flow velocity can be imaged simultaneously. In addition, the flow direction can be determined with bidirectional scanning. In a flowing suspension of red-dyed microspheres (diameter: 6 microm), transverse flow speeds ranging from 0 to 2.5 mms as well as flow direction were measured. A cross-sectional flow image was also obtained with the tube laid in a zigzag pattern.

PMID:
20459226
[PubMed - indexed for MEDLINE]
PMCID:
PMC2857455
Free PMC Article

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