Frequency assessment of 25 SNPs in five different populations

Ilenia Pietrangeli; Enrica Ottaviani; Claudia Martone; Luciano Gabriele; Giovanni Arcudi; Saverio Potenza; Aldo Spinella; Emiliano Giardina; Giuseppe Novelli

doi:10.1016/j.fsigen.2010.01.017

Frequency assessment of 25 SNPs in five different populations

Forensic Sci Int Genet. 2010 Oct;4(5):e131-3. doi: 10.1016/j.fsigen.2010.01.017. Epub 2010 Feb 20.

Authors

Ilenia Pietrangeli¹, Enrica Ottaviani, Claudia Martone, Luciano Gabriele, Giovanni Arcudi, Saverio Potenza, Aldo Spinella, Emiliano Giardina, Giuseppe Novelli

Affiliation

¹ Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, School of Medicine, University of Rome Tor Vergata, Rome, Italy.

PMID: 20457086
DOI: 10.1016/j.fsigen.2010.01.017

Abstract

Allele and genotype frequencies of 25 SNPs previously selected and validated for forensic purposes were assessed in 250 unrelated individuals originating from five different countries of Europe (Spain, Croatia, Bulgaria, Turkey and Serbia). All the SNPs generated extremely low F(st) values confirming our previous results on Italian, African (Benin) and Asian (Mongolian) populations. As a consequence of such F(st) values we observed similar values of random match probability across the populations: 2.26 x 10(-10) in the Spanish population, 2.13 x 10(-10) in the Croatian population, 4.21 x 10(-10) in the Bulgarian population, 2.52 x 10(-10) in the Serbian population and 1.46 x 10(-10) in the Turkish population.

Publication types

Research Support, Non-U.S. Gov't
Validation Study

MeSH terms

Base Sequence
DNA Primers
Forensic Genetics
Genetics, Population*
Humans
Polymorphism, Single Nucleotide*
Probability

Substances

DNA Primers