Med Clin North Am. 2010 May;94(3):465-78.

Cardiovascular consequences of obese and nonobese obstructive sleep apnea.

Source

Division of Pulmonary, Sleep and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, 200 First Street South West, Rochester, MN 55901, USA. ramar.kannan@mayo.edu <ramar.kannan@mayo.edu>

Abstract

Current evidence suggests a role for obstructive sleep apnea (OSA) in the development of cardiovascular disorders. However, obesity is an active confounder in this relationship. OSA and obesity share similar pathophysiologic mechanisms potentially leading to cardiovascular disorders. Presence of OSA in obese patients may further contribute to adverse cardiovascular outcomes when compared with each condition in isolation. In this review the authors explore the complex relationship between OSA and obesity (and nonobese subjects) in the development of cardiovascular disorders.

PMID:: 20451027; [PubMed - indexed for MEDLINE]

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HL99534Z-01/HL/NHLBI NIH HHS/United States

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