Serum proteinogram of cats experimentally infected by Trypanosoma evansi

Prev Vet Med. 2010 Jul 1;95(3-4):301-4. doi: 10.1016/j.prevetmed.2010.04.002. Epub 2010 May 4.

Abstract

This study was aimed at evaluating the electrophoretic profile of serum proteins in Trypanosoma evansi-infected cats during different periods of infection. Thirteen adult females non-breeding Felis catus were separated into two groups. Animals from the infected group (n=7) were inoculated intraperitoneally with a strain of T. evansi; whereas, animals from the control group (n=6) received a physiological solution. Blood samples were collected at days 0, 7, 21, and 35 for total protein evaluation and protein fractionation by electrophoresis. Albumin (P<0.01), alpha-2 globulin and gamma globulin (P<0.05) concentrations were statistically different from the seventh day post-inoculation onwards. Beta-globulin levels were increased from day 21 onwards (P<0.05). Alpha-1 globulin fraction did not differ statistically. These results indicate that the infection by T. evansi in cats alters the serum protein electrophoretic profile.

MeSH terms

  • Animals
  • Blood Protein Electrophoresis / veterinary
  • Blood Proteins / analysis*
  • Cat Diseases / blood*
  • Cat Diseases / parasitology
  • Cats
  • Female
  • Hemoglobins / analysis
  • Serum Globulins / analysis
  • Trypanosomiasis / blood
  • Trypanosomiasis / veterinary*

Substances

  • Blood Proteins
  • Hemoglobins
  • Serum Globulins