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Eur Radiol. 2010 Oct;20(10):2381-9. doi: 10.1007/s00330-010-1800-0. Epub 2010 May 4.

MR elastography of the liver at 3 T with cine-tagging and bending energy analysis: preliminary results.

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  • 1Department of Radiology, Gifu University Hospital, 1-1 Yanagido, 501-1194, Gifu, Japan. haruwow860@yahoo.co.jp

Abstract

OBJECTIVE:

To preliminarily evaluate the feasibility and usefulness of MR elastography of the liver at 3 T with cine-tagging and bending energy (BE) analysis for the evaluation of hepatic fibrosis.

MATERIALS AND METHODS:

Twenty-two patients underwent MR elastography with four different cine-tagging grids on the liver (16- or 20-mm sagittal or coronal). Nine images serially obtained during 1-s of exhalation were analyzed to define coordinates of grid intersections. BE values were calculated using the thin-plate spline method. BE values were compared among patient groups with different fibrosis stage thresholds.

RESULTS:

In the 22 patients, six had a fibrosis score of F0, one had F1, seven had F2, three had F3, and five had F4. Mean BE value with 16-mm sagittal grid was greater with fibrosis score F0 (1.54 ± 0.63) than with ≥F1 (0.97 ± 0.12, P = 0.013) as well as with ≤F1 (1.48 ± 0.60) than with ≥F2 (0.96 ± 0.36, P = 0.019).

CONCLUSION:

Our results showed that MR elastography with 16-mm sagittal grid and BE analysis had a potential in discrimination for the patients with moderate or advanced hepatic fibrosis from those with healthy liver or slight fibrosis.

PMID:
20440504
[PubMed - indexed for MEDLINE]
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