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Neuroradiology. 2010 Jun;52(6):549-53. doi: 10.1007/s00234-010-0697-2. Epub 2010 May 4.

Common and unusual craniofacial manifestations of metastatic neuroblastoma.

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  • 1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA.


Although neuroblastoma is a common childhood malignancy, which frequently metastasizes, involvement of the facial bones and paranasal sinuses are uncommonly reported in the literature. However, over the last several years, we have encountered an increasing number of cases of metastatic neuroblastoma to the central nervous system and head and neck. This article will review the common and uncommon imaging manifestations of metastatic neuroblastoma, with emphasis on the orbits, maxillofacial bones, and paranasal sinuses.

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