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J Occup Environ Med. 2010 May;52(5):561-5. doi: 10.1097/JOM.0b013e3181dd086b.

Is job-related stress the link between cardiovascular disease and the law enforcement profession?

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  • 1Department of Kinesiology, Institute for Social and Behavioral Research, Iowa State University, Ames, Iowa, USA.



To determine whether job-related stress is associated with alterations in pro- and anti-atherogenic inflammatory mediators among law enforcement officers.


Markers of vascular inflammation and the self-reported stress measures of perceived stress, vital exhaustion, job strain, effort-reward imbalance, and social support were compared between officers (N = 444) and non-officers (N = 166).


Officers had higher levels of IL-1beta, IL-6, IL-10, and TNF-alpha and lower levels of C-reactive protein and fibrinogen. No more than 4% of the variability in any of the inflammatory mediators was explained by any stress measure for either the two groups or the entire sample.


Law enforcement officers may be at an increased risk for cardiovascular disease due to a relatively greater pro-inflammatory vascular environment. However, this increased risk cannot be attributed to either chronic stress or the work-related stress measures assessed here.

[PubMed - indexed for MEDLINE]
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