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Department of Histopathology, Sheffield Children's Hospital NHS Foundation Trust, Western Bank, Sheffield, S10 2TH, United Kingdom. mudher.al-adnani@sch.nhs.uk
We present 4 cases of sudden infant death in which we believe that gastroesophageal reflux (GOR) was a contributory, if not a causative, factor. Two of our patients had documented GOR reflux disease during life, and all 4 cases showed histologic evidence of GOR. No other cause of death was identified in any of the patients. Gastroesophageal reflux can cause sudden death in a vulnerable infant during a critical period of development through failure of "autoresuscitation" mechanisms.
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