J Clin Microbiol. 2010 Jul;48(7):2582-5. Epub 2010 Apr 28.

International multicenter study to assess a panel of reference materials for quantification of simian immunodeficiency virus RNA in plasma.

Ham C, Srinivasan P, Thorstensson R, Verschoor E, Fagrouche Z, Sernicola L, Ramos A, Titti F, Almond N, Berry N.

Source

Division of Retrovirology, NIBSC/HPA, South Mimms, Potters Bar, Hertfordshire, United Kingdom.

Abstract

An international multicenter study was conducted to assess the performance of a panel of simian immunodeficiency virus (SIV) RNA reference materials for plasma viral load determinations. Reliable quantification was demonstrated across an approximately 6 log(10) dynamic range. Availability of external reference materials will enable independent calibration of SIV plasma viral load assays.

PMID:: 20427693; [PubMed - indexed for MEDLINE]
PMCID: PMC2897500

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RNA, Viral

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