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Nano Lett. 2010 May 12;10(5):1812-6. doi: 10.1021/nl100499x.

Carbon nanotube transistor controlled by a biological ion pump gate.

Author information

  • 1Molecular Biophysics and Functional Nanostructures Group, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA, USA.

Abstract

We report a hybrid bionanoelectronic transistor that has a local ATP-powered protein gate. ATP-dependent activity of a membrane ion pump, Na(+)/K(+)-ATPase, embedded in a lipid membrane covering the carbon nanotube, modulates the transistor output current by up to 40%. The ion pump gates the device by shifting the pH of the water layer between the lipid bilayer and nanotube surface. This transistor is a versatile bionanoelectronic platform that can incorporate other membrane proteins.

PMID:
20426455
[PubMed - indexed for MEDLINE]
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