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Nucleic Acids Res. 1991 May 25;19(10):2539-66.

Organization of restriction-modification systems.

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  • 1New England Biolabs, Inc., Beverly, MA 01915.

Abstract

The genes for over 100 restriction-modification systems have now been cloned, and approximately one-half have been sequenced. Despite their similar function, they are exceedingly heterogeneous. The heterogeneity is evident at three levels: in the gene arrangements; in the enzyme compositions; and in the protein sequences. This paper summarizes the main features of the R-M systems that have been cloned.

PMID:
2041731
PMCID:
PMC328170
[PubMed - indexed for MEDLINE]
Free PMC Article
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