A highly selective lead sensor based on a classic lead DNAzyme

Chem Commun (Camb). 2010 Jun 14;46(22):3896-8. doi: 10.1039/b926910j. Epub 2010 Apr 20.

Abstract

A catalytic beacon sensor for Pb(2+) has been developed based on the first DNAzyme discovered in the field, and such a sensor has shown a much higher metal ion selectivity (40,000 times) than the previously reported Pb(2+) sensor based on 8-17 DNAzyme and thus is suitable for a wider range of practical applications.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • DNA, Catalytic / chemistry*
  • DNA, Catalytic / metabolism
  • Environmental Pollutants / analysis
  • Fluorescent Dyes / chemistry
  • Lead / analysis
  • Metals / chemistry

Substances

  • DNA, Catalytic
  • Environmental Pollutants
  • Fluorescent Dyes
  • Metals
  • Lead