The hidden rhythms of the dividing cell

Cell. 2010 Apr 16;141(2):224-6. doi: 10.1016/j.cell.2010.03.042.

Abstract

The cell divides in a series of discrete steps that occur in a specific order. Lu and Cross (2010) now propose that cell-cycle events are ordered by a regulatory system in which a master oscillator, based on cyclin-dependent kinases, entrains a series of peripheral oscillators controlling individual events.

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