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J Clin Anesth. 2010 May;22(3):164-8. doi: 10.1016/j.jclinane.2009.05.006.

Apneic oxygenation during prolonged laryngoscopy in obese patients: a randomized, controlled trial of nasal oxygen administration.

Author information

  • 1Department of Anesthesiology, University of Michigan Medical Center, Ann Arbor, MI 48109-0048, USA. rsatyak@med.umich.edu

Abstract

STUDY OBJECTIVE:

To evaluate the influence of nasal oxygen (O(2)) administration on the duration of arterial oxygen saturation (SpO(2)) >or=95% during simulated difficult laryngoscopy in obese patients.

DESIGN:

Prospective, randomized, controlled trial.

SETTING:

University hospital.

PATIENTS:

30 obese men undergoing general anesthesia.

INTERVENTIONS:

After thorough preoxygenation, and using total intravenous anesthesia, simulated difficult laryngoscopy was performed, with half the patients receiving additional nasal O(2) during apnea.

MEASUREMENTS:

Duration of SpO(2) >or=95% was measured up to a maximum of 6 minutes. Lowest SpO(2) values and time to regain 100% SpO(2) (resaturation time) also were recorded.

MAIN RESULTS:

Nasal O(2) administration was associated with significant prolongation of SpO(2) >or=95% time (5.29 +/- 1.02 vs. 3.49 +/- 1.33 min, mean +/- SD), a significant increase in patients with SpO(2) >or=95% apnea at 6 minutes (8 vs. one pt), and significantly higher minimum SpO(2) (94.3 +/- 4.4% vs. 87.7 +/- 9.3%). Resaturation times were no different between the groups.

CONCLUSIONS:

Nasal O(2) administration is associated with significant increases in frequency and duration of SpO(2) >or=95%, and higher minimum SpO(2) during prolonged laryngoscopy in obese patients.

(c) 2010 Elsevier Inc. All rights reserved.

PMID:
20400000
[PubMed - indexed for MEDLINE]
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