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CNIO (Spanish National Cancer Centre), Melchor Fernandez Almagro 3, 28029 Madrid, Spain.
Ras proteins play important protumorigenic roles by activating multiple signaling pathways. A study in this issue of Molecular Cell (Shin et al., 2010) dissects the implications of ERK2 signaling downstream of oncogenic Ras in the induction of epithelial-to-mesenchymal transition (EMT), cell motility, and invasion.
2010 Elsevier Inc. All rights reserved.
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