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Nutr Rev. 2010 Mar;68(3):178-81. doi: 10.1111/j.1753-4887.2010.00274.x.

Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation?

Author information

  • 1Vitamin K Laboratory, USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachussetts 02111, USA. sarah.booth@tufts.edu

Abstract

Numerous risk factors for instability of oral anticoagulation have been identified, including variability in vitamin K intake. However, few studies have directly tested the feasibility of manipulating dietary vitamin K to achieve stable oral anticoagulation. Recent findings from a randomized clinical trial suggest that dietary vitamin K manipulation is a viable option for managing stability of oral anticoagulant therapy. The approach appears to be effective for those patients who are under-anticoagulated and consume a small number of vitamin K-rich food sources. While an encouraging option for management of warfarin therapy, longer-term studies in different patient populations are required.

PMID:
20384848
[PubMed - indexed for MEDLINE]
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