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Eur Arch Otorhinolaryngol. 2010 Jun;267(6):991-4. doi: 10.1007/s00405-010-1234-y. Epub 2010 Apr 10.

Laryngeal dedifferentiated liposarcoma.

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  • 1Head and Neck Surgery Department, CHU Montpellier, Montpellier, France.



Soft tissue liposarcomas are quite common in the adult population, whereas liposarcoma of the larynx is exceedingly rare.


We describe an exceptional case of liposarcoma of the posterior aspect of the left arytenoid in a 62-year-old woman who was treated with two endoscopic excisions and adjuvant radiotherapy (RT). This is the 32nd case of laryngeal liposarcoma reported in the English literature.


After a 20 months follow-up, no local, regional recurrences or distant metastases were detected, and no functional complications are described for the patient.


This case report highlights that endoscopic surgical treatment enables excellent organ and functional preservation. However, recurrence of laryngeal liposarcoma is the principal risk, so extended follow-up is essential. RT has no defined role in treatment but can be discussed, especially considering the surgical margins and recurrence status.

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