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J Electrocardiol. 2011 Jul-Aug;44(4):483-6. doi: 10.1016/j.jelectrocard.2010.02.009. Epub 2010 Apr 9.

High risk of sudden death associated with a PRKAG2-related familial Wolff-Parkinson-White syndrome.

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  • 1The Second Hospital of Lanzhou University, Lanzhou, China.

Abstract

Familial appearance of Wolff-Parkinson-White (WPW) syndrome is rare and displays an autosomal dominant inheritance. Here we report a Chinese kindred of WPW syndrome whose unique clinical features consist of a high risk of sudden cardiac death due to atrial fibrillation, causing a rapid antegrade conduct over the accessory pathway. The mutation in the PRKAG2 gene was identified as responsible for the familial form of WPW syndrome.

Copyright © 2011 Elsevier Inc. All rights reserved.

PMID:
20381067
[PubMed - indexed for MEDLINE]
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