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Epidemiol Infect. 2010 Nov;138(11):1630-6. doi: 10.1017/S0950268810000695. Epub 2010 Apr 12.

Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007.

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  • 1Programme on Infectious Disease and Vaccine Sciences, Health System and Infectious Disease Division, Institute of Epidemiology, Disease Control and Research (IEDCR) Dhaka, Mohakhali, Bangladesh. nhomaira@icddrb.org

Abstract

In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 9.5%, OR undefined, P<0.001) and to have touched him (83% vs. 0%, OR undefined, P<0.001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.

PMID:
20380769
[PubMed - indexed for MEDLINE]
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