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J Indian Soc Periodontol. 2009 Sep;13(3):121-5. doi: 10.4103/0972-124X.60223.

Is anti-platelet therapy interruption a real clinical issue? Its implications in dentistry and particularly in periodontics.

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  • 1Department of Periodontics, Sri Sai College of Dental Surgery, Vikarabad, Andhra Pradesh, India.


The use of anti-platelet therapy has reduced the mortality and morbidity of cardiovascular disease remarkably. A considerable number of patients presenting before a dentist or periodontist give a history of anti-platelet therapy. A clinical dilemma whether to discontinue the anti-platelet therapy or continue the same always confronts the practitioner. Diverse opinions exist regarding the management of such patients. While one group of researchers advise continuation of anti-platelet therapy rather than invite remote, but possible, thromboembolic events, another group encourages discontinuation for variable periods. This study aims at reviewing the current rationale of anti-platelet therapy and the various options available to a clinician, with regard to the management of a patient under anti-platelet therapy. Current recommendations and consensus favour no discontinuation of anti-platelet therapy. This recommendation, however, comes with a rider to use caution and consider other mitigating factors as well. With a large number of patients giving a history of anti-platelet therapy, the topic is of interest and helps a clinician to arrive at a decision.


Anti-platelet therapy; decision-making; dental and periodontal treatment

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